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The metformin component of glucovance mite is bioequivalent to metformin coadministered with glyburide.

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If you are already taking another diabetes drugsuch as chlorpropamidefollow your doctor’s directions carefully for stopping the old drug and starting this combination medication.

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If you also take colesevelamavoid taking it within 4 hours after you take Glucovance.

Take Glucovance exactly as prescribed by your doctorFollow all directions on your prescription label and read all medication guides or instruction sheetsYour doctor may occasionally change your doseUse the medicine exactly as directed.

There was no evidence of mutagenic potential of glyburide alone in the following in vitro testsSalmonella microsome testAmes testand in the DNA damage/alkaline elution assay.

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